Trends in Pharmacogenetics
نویسندگان
چکیده
منابع مشابه
Pharmacogenetics in Practice Pharmacogenetics in Cardiology: Forays into Modern Practice
When one discusses pharmacogenetics in cardiology practice, it is almost obligatory to discuss clopidogrel. Clopidogrel is an antiplatelet used for acute coronary syndrome (ACS), percutaneous coronary intervention (PCI) with stenting, and as secondary stroke prevention in patients with aspirin allergy, among other indications. Clopidogrel is a prodrug that must be metabolized through the cytoch...
متن کاملPharmacogenetics in biological perspective.
What have we learned? Pharmacogenetics, heritable variation in response to xenobiotics, is present in all forms of life. Initially, human data perhaps have created the most excitement, and they provide much biochemical detail. However, if we look at pharmacogenetic variation of insects and bacteria, we see it as a characteristic of populations; individuals with inborn resistance to various toxi...
متن کاملPharmacogenetics in pancreatic cancer.
Pancreatic cancer is an aggressive malignancy with a poor overall survival rate. Given advances in pharmacogenomics, numerous gene mutations have been identified that could be potential targets for drug development. Therefore, future research strategies may identify prognostic and predictive markers aiming to improve outcome by maximizing efficacy whilst lowering toxicity. In this commentary, w...
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Pharmacogenetics is an emerging discipline that attempted to understand the hereditary basis for differences in responsiveness or inter-individual variation to therapeutic agents. It is the study of variability in drug response as a result of heredity factors. The importance for pharmacogenetics for the clinician is to enable optimum therapeutic efficacy, to avoid toxicity of those drugs whose ...
متن کاملExperimental Pharmacogenetics
Furthermore, Dr. Moulder is able to make the reader realize that the problem has considerable theoretical and practical value and is not just an exercise in semantics. It is a stimulating book. Investigators in a wide variety of fields will find this short volume an extremely useful reference book. The purpose of the monograph was to bring together the known biochemical and structural inherited...
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ژورنال
عنوان ژورنال: Biomedical Journal of Scientific & Technical Research
سال: 2018
ISSN: 2574-1241
DOI: 10.26717/bjstr.2018.11.002073